I have 4 normal Otos in the main tank, will these be enough to provide companionship to the now lonely Zebra Oto?
I have a zebra otto with 3 other regular ones which also are mixed breed and the 4 of them hang out together when not browsing for food so your otto will be happy enough with non-zebra buddies.
They are not any more sensitive than the rest.
For quarantine I sometimes use my small tank. It's heavily planted/soil tank with some cherry shrimp so it's technically always cycled and suitable for any sensitive small fish. My new ottos bred in it within 3 weeks of purchase.
But same as Edvert, I believe the most important is an established tank with the right environment and if I can't provide one via a ready quarantine tank then I don't quarantine. And in fact I've been lucky to never introduce any diseases either. Same as Edvert I have never seen ich in my tanks. I've added clown loaches twice in one of my tanks and they are notorious for getting ich when introduced. Some people swear they do get ich each time and I was advised to treat just in case but I don't add meds to my tanks because of fear. Meds can be more dangerous than the diseases.
I believe one has to provide the least stressful and healthy environment because adding an immune system compromised fish to an uncycled tank for example, or a tank too small, or too bare, or moving/catching fish twice within the space of a month or two after they just possibly got used of the tank, isn't going to help them resist the environmental bacs and parasites lurking in all tanks which is why 90% of the time fish get sick in the first place. Fish with primary diseases that are highly contagious will be most likely already sick when you see them in the shop, or dead within a few days so to avoid that you just need to let the shop quarantine/wait after they brought them in. Other famous dangerous diseases like camallanus worms or micobacteria/fish tb take months to show so unless you quarantine for 3-6 months to a year and be extremely careful when working on multiple tanks, the chances are your other tanks will be infected whether you like it or not, and whether you use quarantine or not.
A true quarantine tank has to be very established, in a totally different room from the rest of your tanks, with it's own devices/nets/hoses/buckets for water changes and extremely diligent procedures for disinfecting yourself/hands before touching anything else after working in the quarantine tank, including door knobs
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So I don't stress about diseases. I observe the fish in the shop, also the inhabitants with them. I ask how long they've been in the shop, etc.... I normally do a large water change on the target tank, then buy the fish, drip acclimate for 1-2 hrs, then add the fish, then feed everyone so the previous occupants don't get too curious and normally the new fish feel like at home immediately.