With fish, picking a treatment is a lot more based on anecdotal recommendations, we're talking about hundreds of species that can react differently and the environmental conditions play a part in the effectiveness. I'm not confident in what to give that's both effective and definitely not harmful so I err on the side of only treating when there is a visible issue.
There is loads of ornamental fish data but it tends to be buried in rather technical tomes (limited publications designed for veterinary programs, even most libraries are uninterested in investing) or non-open online research groups/journals
Noga’s book is much more affordable now
Fish Disease: Diagnosis and Treatment, 2nd Edition
Edward J. Noga
(I’ve tried to encourage my local library to replace their (surprisingly useless) current book selection with this (more technical) book and the Manual Of Fish Health (general readership)
🙄
Beginning with the very approachable Manual of Fish Health, then reading through the Fish Health & Aquaculture Articles available through University of Florida EDIS extension (and other American universities, though some only host UofF articles) will give a good background (included are basics of treating fish with antibiotics etc and what steps should be taken to minimize stress and maximize medication efficacy)
BUT
many of the proven medications are unavailable to hobby fish keepers - either through cost or regulations - and very few veterinary clinics are set up to handle ornamental fish enquires
Effective treatment of fish illness often depends on identification of the dominant pathogen (fish do secondary infections like nobody’s business
😱) and at the stage when it’s early enough for effective treatment
Hobby fish keepers usually only really notice (ie begin active research) for fish illness after fish are no longer eating - at which point the disease is well advanced - or visible lesions/abnormalities are seen on fish fins/skin (these are often secondary infections)
Stress dramatically suppresses fish immune system (well documented if you want to go digging
😉) and pathogens that are part of their “normal flora” can transition very quickly to disease states
(As I recall the Manual of Fish Health has a decent chapter on fish stressors)
When selecting suitable online articles for treating fish, I suggest leaning towards those dealing with Zebra danios rather than Channel Catfish
😉 (or salmonids
)
Preventative treatments for common pathogens such as ich, tend to be reasonable treatments rather than unnecessary stress - again look at recent articles discussing ich prevalence on (ornamental) fish production farms of even wild caught South American fish species, then add in the stress of shipping & (possible multiple) temporary holding stations
(again there is data for pathogens present at the start of the journey, and then pathogens present at journey’s end)
Some wild caught fish species react adversely to medications, especially bath treatments, again there are alternate protocols discussions (trials)